In Parallel to characterising the conversation in between conolidine and ACKR3, the two teams went a step more. The researchers formulated a modified variant of conolidine — which they called “RTI-5152-twelve” — which exclusively binds to ACKR3 with a good larger affinity. Like LIH383, a patented compound previously made by https://www.proleviate.com/post/is-conolidine-a-real-pain-reliever