Introduction: Patency installation of IV line is band resilience installation of good IV line of place location of insersion husk and also around installation location. Based on CDC ( Centers for Disease Control ) recommendation IV line replacement time is 72 hours ( 3 days ). In neonates. the replacement of the IV line often happened before the third day. https://www.chiggate.com/chromatics-6nn-6-0-natural-ultra-rich-cheap/