Epithelial ovarian carcinoma (EOC) is the most lethal gynecological malignancy. Herein. we sought to determine the efficacy of phosphoinositide 3-kinase (PI3K)/Akt inhibition using three AZD compounds in a NOD-SCID xenograft mouse model and Akt regulation in a panel of eight ovarian cancer cell lines. Elevated Akt phosphorylation on Ser473 but not on Thr308 in cancerous tissues correl... https://darthomes.shop/product-category/holiday-ornaments/