ABSTRACT Inflammatory responses. while essential for pathogen clearance. can also be deleterious to the host. Chemical inhibition of topoisomerase 1 (Top1) by low-dose camptothecin (CPT) can suppress transcriptional induction of antiviral and inflammatory genes and protect animals from excessive and damaging inflammatory responses. https://countryscenesaddleryandpetsuppliers.shop/product-category/wade-western-saddle/